Coating pans are worn to shape an aqueous or untreated film approximately any variety of tablet and drug or micro granule. These pans are moreover expansively worn to sugar-coat tablets. A coating pan is an essential prerequisite in pharmaceutical request. Dissimilar coating technique is functional in pharmaceutical business. Coating Pans have been intended after a cautious learns of the wants of specialist such as gyratory Speed, Angle of leaning of pan quantity and temperature. In the procedure of finish tablets and confectionaries, the individual skill of the coater needs to be supplement by a rightly intended, adaptable coating pan.
Operation Principles
Pellets/Tablets are continuously feed into a finish drum at a controlled rate. An elevated quantity of progression air heats the tablets at the instance of incoming and affecting in the drum. Coating explanation is functional from side to side a sequence of spray guns as the produce moves downwards the duration of the coating drum. The drug is consistently varied for a standardized coating/weight gain. Low bed depth of the pan permit the tablet/pellets to pass from side to side the spraying zone and ultimately discharge from the fatigue end of the coating drum and elated through a conveyor belt for compilation, storage space, assessment and wrapping. This machinery ensures reliable external coating.
A coating is a covering that is functional to the exterior of an object, frequently referred to as the substrate. The standard of relate the coating may be decorative, sensible, or both. The covering itself may be an all over coating, completely cover the substrate, or it might only wrap parts of the substrate. An occurrence of all of this kind of coating is a construct label on a lot of drinks bottles solitary side has an all-over useful coating and the previous side has one or more decorative coatings in a suitable pattern to form the words and images.
A main deliberation for mostly coating procedure is that the jacket is to be useful at a forced thickness, and a numeral of dissimilar process are in use to attain this direct, variety from a easy brush for painting a wall, to a quantity of very expensive machinery apply coatings in the electronics industry. An additional contemplation for ‘non-all-over’ coatings is that direct is required as to anywhere the coating is to be functional. Numerals of these non-all-over coating processes are printing process.
Tablet coating
Frequent tablets nowadays are coated after being pushed. Even though sugar-coating was conventional in the history, the procedure has many drawbacks. Modern tablet coating is polymer and polysaccharide base, with plasticizers and colour integrated. Tablet shell has to be steady and brawny sufficient to stay alive the demeanour of the tablet, must not make tablets connect equally throughout the coating procedure, and have to go behind the well contour of stamped characters or logos on tablets. Coatings are essential for tablets that contain an unlikeable taste, and a smoother come to an end makes large tablets easier to gulp. Tablet coatings are also helpful to extend the shelf-life of mechanism that is responsive to damp or corrosion. Particular coatings (for example with pearlescent property) can improve product gratitude.
If the energetic constituent of a tablet is receptive to acidic, or is nuisance to the abdomen inside layer, an enteric coating can be worn, which is opposed to to abdomen acidic, and dissolve in the fewer acidic area of the bowels. Enteric coatings are also used for medicine that can be unenthusiastically pretentious by taking a long time to arrive at the small intestine, where they are engrossed. Coatings are frequently selected to manage the speed of dissolution of the medicine in the gastrointestinal tract. A quantity of drugs is engrossed improved in influenced parts of the digestive arrangement. If this constituent is the stomach, a covering is exacting that suspend rapidly and with no complexity in acidic. If the speed of combination is most admirable in the enormous intestine or colon, an exterior layer is worn that is acidic opposed to and disband steadily to make certain that the tablet reach that point proceeding to scatter.
There are two types of outside layer equipment use in the pharmaceutical industry: coating pans and routine coaters. Covering pans are worn mainly to sugar coat pellets. Mechanical coaters are use for all variety of coatings; they can be capable of with an inaccessible control panel, a dehumidifier, and dust collectors. An explosion-proof intends is necessary for apply coatings that contain alcohol
tablet coating machines are cGMP compliant pharmaceutical equipment, featuring the latest automation and energy saving technologies. They are perforated pan coating machines with simplified and precise spraying system for an optimal atomization of the coating solution.
Sugar Coating System, Super Coater, Tablet Coater, Film Coating Machine, Pill Coating Machine, Tablet Film Coater, Pharmaceutical Coating Machine
Centrally positioned baffles ensure the best mixing results while outlet air duct guarantees efficient and uniform drying. Shree Bhagwati tablet coating machines come in different shapes and designs for both film coating and sugar coating.
That is, to classify all the existing tablet coating equipment, depending on the working principle and coating process/technique.
This way, you will get to know the type of tablet coater machine that is suitable for your unique applications.
Now, let go straight to the main subject of this article:
- Types of Tablet Coating Equipment (Main Focus Being the Working Principle)
- Perforated Coating Pan
- Fluidized Bed Coater
- Types of Tablet Coating Machines (Focusing on Coating Process)
Types of Tablet Coating Machines (Focusing on Coating Process)
Well, you can choose a tablet coater system depending on the following key processes:
- Sugar coating: It is the process of covering tablets with a sugar layer that can either be colored or uncolored.
- This coating is soluble, masks bad taste, acts as a protective layer and enhances appearance.
- Film coating: Most drug manufacturers are switching to film coating.
- It is basically the process of adding a very thin layer to tablets.
- Film coating process is easy to automate, involves few procedures and increases the overall weight of tablets by only 3%.
- This is not the case for sugar coating where a tablet may weight more that 30%.
- Enteric coating: It mainly protects tablet core from the acidic environment in the stomach. With enteric coating, the tablet will not disintegrate.
- As you can see, these are basically tablet making processes.
- Coated tablets
- For the scope of this article, I may not be able to discuss each of these tablet coating processes.
Tablet Coating Machine – Tablet Coating Pan, Pan Coating Machine, coating machine in pharmaceutical industry
Pharmaceutical Tablet Coating Machine : Specification
- The tablet coating machine parameter complies with the Goods Manufacturing Practices (GMP) standard
- The machine’s components are quick and easy dismount without the overall use of tools for cleaning and maintenance
- The tablet coating machine construction is compact, allowing it to occupy a small space
- It contains an efficient air inlet and outlet handling system
- The machine can adjust the speed of the coating drum
- The PLC control is suitable as a data activity record is printable for evaluation
- The Pharmaceutical tablet coating machine is built by a type of material that is resistant to corrosion, ensuring continuous tablet coating machine operations and reduction of wear out costs
Parts of a Tablet Coating Machine:
Automated control system : The part controls the various functions automatically, for instance, operation of the machine, and the regulation of speed, pressure, and temperature.
Electric motors : They facilitate various tablet coating machine operations such as blowing air, mixing, and pressure creation.
The touch screen operating panel facilitates observation, the input of controls, and monitoring by an operator with a user-friendly interface.
Guide plate: It allows for the smooth tumbling of the tablets when blowing hot air through them during the drying process.
Peristaltic pump ensures constant pressure in the machine. During the spraying process, the pump aids in the stabilization of the atoms.
Spraying system: Components of this part are the nozzle, tank, and a pump, where it stores the tablet coating solution, ensures atomization stability, cleaning, and maintenance of the spraying pump.The Pan cooling surface consists of an automatic load cell system that helps in regulating the volume of the spraying solution. Its components include the electronic pulse valve, a discharging device, an exhaust dust collector, an air heating unit, and an air distribution device.
Coating preparation tank: The part facilitates the preparation of the coating solution
Working Principle of Pill Coater:
Select the suitable coating materials depending on the kind of tablets you are using and the desired coating. The next process is tablet spinning, whereby the tablets are put in a drum and rotating it in an orbital way, the streamlined plates control most of the operations. As the drum spins, the nozzle sprays a coating solution regulated by an automated control system. The system ensures accuracy and even spray of the coating on the tablets. As the spraying continues, the machine pumps hot air into the drum resulting in a rapid coat of the solution. It self-regulates the same temperature to ensure a good condition of the drugs’ composition. When the desired coating achieves, spinning and spraying ends, the tablets proceed to the drying section where air flows over them. The volume of air is also regulated to ensure no reaction with the pills, and this is how the tablet coating machine works before the packaging process.
Types of Tablet Coating Machines :
There are three types of Tablet Coaters:
Standard coating pan: It consists of a circular metal with a diameter of 6-8 inches. It is slightly tilted 45 degrees to the benchtop and has an electric motor that rotates a metal pan horizontally to its axis. Improper balancing of inlet and exhaust air is a shortcoming experienced, which can be collected by adding components such as immersion tube system, immersion sword, baffled pan, and diffuser.
Perforated coating plan: Consists of either a fully or partially perforated drum and features a horizontal axis rotation of the drum. It displays an efficient drying system and a high tablet coating machine capacity.
Fluidized bed coater: It works by turning material particles for coating into a fluid followed by spraying.
Applications
- Pharmaceutical: For tablets film coating, enteric coating, sugar coating and control released coating.
- Food: Film coating of the agriculture product and healthy food, sugar coating of chewing gum and candy.
- Seed: For insect protection layer or nutrient.
The various types have a ground in the medical industry for pharmaceutical drug manufacturing and the cosmetic industry, where they add color on their products to make them attractive for sales increase.
AUTOMATIC COATER: Pan Size: 30”/36”/42”/48”/60”/66”
| Pan Diameter – Inch(mm) | 30” -750 | 36” -920 | 42” -1070 | 48” – 1220 | 60” – 1525 | 66”-1675 |
| Approx Working Capacity | 30 | 75 | 100 | 150 | 350 | 500 |
Salient Features
- Perforated pans with rabbit-eared baffles
- PLC with HMI
- 21 CFR Part 11 Compliance can be provided
- Recipe Management and Password protection
- Spraying systems spray gun with fan controls.
- Spray angle and distance to the tablet bed can be adjusted.
- Anti bearding spray nozzles provided for efficient spray pattern for coating without beard formation.
- Tablet unloading attachment ensuring discharge of single tablet without manual intervention
Recommended Operations for minimizing coating defects:
Spray rate: A low spray rate results in insufficient wetting, creating a brittle coat while a high spray rate over wets the tablets making them too sticky. Ensure the right spray rate before you begin the operations.
Air capacity: Air aids in drying the coated tablet, ensure sufficient air supply to prevent the occurrence of defects.
Coating composition: The operator must caution the proper mixing of materials to prevent defects such as a blockage.
Rotation speed should not exceed optimum levels, and to achieve proper equipment efficiency, ensure all other components are operating at optimum levels under appropriate regulation of the processes.
Film coating: A thin layer of a film-forming polymeric is deposited onto a product substrate in the process of film coating. The procedure can be carried out with standard panning equipment, but modern equipment is more advanced in order to provide effective drying, a high level of automation, and quick coating.
Film coating is a typical process in the production of tablets and can be used to enhance the product’s appearance, organoleptic qualities, or swallowing convenience. Functional film coats can also be utilized to adjust or postpone drug release as part of the product’s stabilization strategy.
Sugar coating: In quick release applications, sugar coating is used to hide the undesirable flavor and odor of some medications or to enhance the product’s visual characteristics. It is important to realize that the coating procedure may affect how quickly a medicine dissolves while also delaying the overall disintegration of the tablet.
The sugar coating serves as a barrier to external pollutants and safeguards the medication inside the tablet, among other functions.
Optional Devices Are Available
- Explosion proof system (Organic solvent is applicable).
- WIP or CIP system.
- Touch Screen Interface control system.
- Temperature recorder.
- Dehumidifier device.
- Dust collector system (Wet or Dry types).
- High accuracy air volume / pressure measuring device.
- Weighing system (To observe the changing of the solution).
- Preparation tank.